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Iron (Serum or Plasma Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron present in your blood serum or plasma, which helps assess iron stores and identify deficiencies or excesses.

Quick summary

["Iron levels help diagnose or monitor iron-related health issues like anemia or hemochromatosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
35214-6
Short code
Iron SerPl-msCnc
Synonyms
Iron SerPl-msCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83540
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms of iron deficiency, such as fatigue, pale skin, or weakness, or if you have conditions like anemia, gastrointestinal bleeding, or excessive blood donation. It may also be used to check for iron overload in conditions like hemochromatosis or during pregnancy to ensure proper fetal development.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves a blood draw. Avoid taking iron supplements or certain medications (like antacids) for 24 hours before testing, as they can affect results.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab for analysis using a method like chemiluminescence or immunoassay to measure iron concentration.

What Do the Results Mean?

Results are compared to reference ranges, but exact values can vary by lab. Low iron levels may indicate anemia or poor absorption, while high levels may signal iron overload or certain medical conditions. Your provider will interpret results in the context of your symptoms and medical history.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low iron levels (hypoferremia) are often linked to iron deficiency anemia, which can cause fatigue, weakness, and impaired cognitive function. High iron levels (hyperferremia) may indicate hemochromatosis, liver disease, or repeated blood transfusions. Monitoring iron levels helps prevent complications and guides treatment, such as dietary changes or medication.

Short name

Iron Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab and testing method. Your provider will contact you once they are ready to discuss the findings.
Can I take iron supplements before or after this test?
Avoid taking iron supplements for at least 24 hours before your test, as they can skew results. If you must take them, inform your healthcare provider immediately.
Does this test require fasting?
Some tests involving blood draws may require fasting for 8–12 hours, but iron tests alone do not. Follow your provider’s specific instructions for your appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy