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Iron, Serum or Plasma Mass Concentration (Iron Saturation or Total Iron-Binding Capacity Indirectly Related)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron in your blood, which is important for making red blood cells and keeping your body healthy. Iron is a mineral that helps carry oxygen in your blood.

Quick summary

["Iron levels help doctors check if you have too much or too little iron in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
53456-0
Short code
Iron Spec-mCnt
Synonyms
Iron Spec-mCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83540
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to diagnose or monitor conditions such as anemia (low red blood cells), iron overload, or iron deficiency. It can also help check for certain blood disorders or nutritional deficiencies.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from your arm. If you have a urine test, you might need to collect a sample at home or in a clinic.

What the Test Involves

Blood is drawn from a vein in your arm, or you may provide a urine sample depending on the test type. The sample is then sent to a lab for analysis.

What the Results Mean

Results can indicate whether your iron stores are adequate, too high, or too low. While reference ranges vary by lab, abnormal results may prompt further testing or treatment to address potential conditions like anemia or iron overload.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Iron levels

Frequently asked questions

What does a low iron level mean?
A low iron level may suggest iron deficiency, which can cause fatigue, weakness, or pale skin. Your doctor may recommend dietary changes, supplements, or other treatments to increase iron intake.
What does a high iron level mean?
High iron levels can lead to iron overload, which may cause organ damage over time. This condition is more common in people with certain genetic disorders or those who consume excessive iron supplements.
How often should I get this test?
Your doctor will determine how often you need this test based on your health, symptoms, and medical history. Regular monitoring may be recommended if you have conditions like anemia or iron-related disorders.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy