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Iron, Total Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron present in your blood serum. Iron is an essential mineral your body needs to make hemoglobin, which carries oxygen in your red blood cells.

Quick summary

["Iron levels help assess your risk for anemia or iron deficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
15357-7
Short code
Iron Tiss-mCnt
Synonyms
Iron Tiss-mCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83540
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, pale skin, weakness, or shortness of breath—common signs of low iron. They might also order it to check for iron overload if you have conditions like hemochromatosis or frequent blood donations.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel, but this isn’t always required for just the iron test. Bring any medications you’re taking to your appointment.

How the Test Is Done

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are compared to standard ranges for your age, sex, and overall health. Low iron levels may indicate anemia or poor absorption, while very high levels could suggest conditions like hemochromatosis or excessive intake.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low total iron levels often point to iron deficiency anemia, which can cause fatigue, weakness, and an increased risk of infections. High levels may signal iron overload, which can damage organs over time. This test is a key part of diagnosing and managing these conditions, especially in patients with symptoms or risk factors.

Short name

Total Iron

Frequently asked questions

How long does it take to get my iron test results?
Results are typically available within 1–3 business days, depending on your lab’s processing schedule. Follow up with your healthcare provider if you have questions about your results.
Can I eat or drink anything before this test?
Most of the time, no fasting is required for just the iron test, but check with your provider if it’s part of a larger panel. If you’re unsure, ask for clarification before your appointment.
What causes low iron levels?
Low iron can result from poor diet (low intake of iron-rich foods), chronic blood loss (like heavy periods or digestive issues), or increased demand (such as pregnancy or rapid growth). Certain medical conditions, like celiac disease or inflammatory bowel disease, may also contribute.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy