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Iron (Serum or Plasma) Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron present in your blood serum or plasma, which helps assess iron stores and potential deficiencies or excesses.

Quick summary

["Iron levels help identify anemia, iron overload, or nutritional deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2504-9
Short code
Iron Ur-mCnc
Synonyms
Iron Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83540
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for iron deficiency (which can cause fatigue, weakness, or pale skin) or iron overload (which may lead to organ damage). It’s often done when symptoms like unexplained fatigue, unusual tiredness, or signs of anemia appear. It can also be part of routine blood work or screening for conditions like hemochromatosis (iron overload) or hemochromatosis-related disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic or liver evaluation. Bring any medications you’re taking, as some (like iron supplements) can affect results. If you’re pregnant, let your provider know—iron levels can vary during pregnancy.

During the Test

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it’s usually over quickly. The blood sample is sent to a lab for analysis. The process takes about 15 minutes total.

What the Results Mean

Results are compared to standard ranges for your age, gender, and overall health. Low iron levels may indicate anemia or poor absorption, while very high levels could signal conditions like hemochromatosis or excessive intake. Your provider will discuss the results in the context of your symptoms and medical history.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: urine

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Iron levels are critical for red blood cell production and oxygen transport. Low iron can cause anemia, leading to fatigue, weakness, or shortness of breath. High iron levels may damage organs over time, especially in conditions like hemochromatosis. Regular monitoring is important for people with genetic risks or those who have had repeated blood transfusions.

Short name

Iron Level

Frequently asked questions

How often should I get this test?
Your provider will determine how often you need this test based on your symptoms, medical history, and risk factors. For example, people with known iron deficiency or hemochromatosis may need monitoring every few months or annually. Routine adults without symptoms may not need it unless recommended by their doctor.
What are common symptoms that might lead to this test?
Common symptoms prompting this test include persistent fatigue or weakness, pale or yellowish skin, brittle nails, unexplained weight loss, or frequent infections. If you have a family history of iron-related disorders (like hemochromatosis) or conditions like celiac disease or celiac disease-related malabsorption, your provider may also recommend it.
Can I take iron supplements if my iron level is low?
Iron supplements can help raise low iron levels, but they should only be taken under medical supervision. Taking too much iron can cause side effects like nausea, stomach pain, or organ damage over time. Your provider will guide you on dosage and timing to avoid interference with other medications or nutrients.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy