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Iron (Serum or Plasma Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron present in your blood, which is important for making hemoglobin—the protein in red blood cells that carries oxygen throughout your body.

Quick summary

["Iron helps prevent anemia and supports overall energy levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
53501-3
Short code
Iron Wat-sCnc
Synonyms
Iron Wat-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83540
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Iron Used For?

Iron is a vital mineral that plays a key role in producing hemoglobin, the protein in red blood cells that carries oxygen from your lungs to the rest of your body. It also helps with energy production, immune function, and muscle movement. Low iron levels can lead to fatigue, weakness, or anemia, while high levels may cause health risks like organ damage or heart problems.

Why Might You Need This Test?

Your doctor may order an iron test if you have symptoms like extreme fatigue, pale skin, shortness of breath, or unusual cravings for non-food items (pica). It’s also used to diagnose or monitor conditions such as anemia, pregnancy, heavy menstrual bleeding, or certain medical treatments that affect iron absorption.

How Is the Test Performed?

A small blood sample is taken from a vein in your arm. The sample is sent to a lab, where it is analyzed to measure the iron concentration in your serum or plasma. Results are typically available within a few days.

What Do the Results Mean?

Results are compared to standard reference ranges, which can vary by lab. Low iron levels may indicate anemia or poor absorption, while high levels may suggest conditions like hemochromatosis or excessive iron intake. Your doctor will interpret results in the context of your symptoms and medical history.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

How Does Iron Affect My Health?

Short name

Iron Level

Frequently asked questions

What causes low iron levels?
Low iron levels can result from conditions like heavy menstrual bleeding, poor diet (low in iron-rich foods), pregnancy, or certain medical conditions (e.g., celiac disease, stomach ulcers). It can also occur if your body doesn’t absorb iron properly or if you lose too much blood.
What causes high iron levels?
High iron levels may be caused by genetic disorders (like hemochromatosis), excessive iron supplements, repeated blood transfusions, or certain liver diseases. Chronic alcohol use can also contribute to iron overload.
How often should I get this test?
Your doctor will determine how often you need this test based on your symptoms, medical history, and treatment plan. Regular monitoring may be recommended if you have anemia, a history of iron-related conditions, or are taking iron supplements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy