Autoantibody Panel to Screen for Islet Cell Antibodies (Serum)
This test measures antibodies that may indicate an autoimmune response targeting insulin-producing cells in the pancreas, often linked to type 1 diabetes.
["This screening helps detect early signs of autoimmune conditions affecting insulin production."]
Key facts at a glance
- LOINC
- 56718-0
- Short code
- Islet Cell512 Ab Ser IA-aCnc
- Synonyms
- Islet Cell512 Ab Ser IA-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Autoimmune diseases like type 1 diabetes can develop when the immune system mistakenly attacks healthy cells. This test checks for specific antibodies (islet cell antibodies) that may signal this process in the pancreas. While not all positive results mean diabetes, they can prompt further evaluation.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm. The test is usually done in a lab setting and may take a few minutes. Results are often available within a few days.
What the Results Mean
A positive result suggests the presence of islet cell antibodies, which may indicate an autoimmune response. This doesn’t confirm diabetes but can guide further testing, such as C-peptide levels or genetic screening. False positives can occur, so follow-up with your healthcare provider is important.
Common Causes of Positive Results
Positive results are most commonly associated with type 1 diabetes, but they can also appear in other autoimmune conditions or during early stages of the disease. Rarely, they may be found in people without diabetes or autoimmune issues.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Islet Cell Antibody Screen
Frequently asked questions
What does a positive result imply?
Can this test predict diabetes?
What if my results are positive but I don’t have symptoms?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy