Total Isocyanate Exposure Level (Serum)
This test measures the total level of isocyanates, a group of chemicals used in adhesives, coatings, and sealants, in your blood serum. Isocyanates can cause allergic reactions and respiratory issues.
["Assesses potential exposure to harmful isocyanate chemicals in your blood."]
Key facts at a glance
- LOINC
- 61277-0
- Short code
- Isocyanate HDI IgE/IgE total %
- Synonyms
- Isocyanate HDI IgE/IgE total %
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 86038
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
This test is done to find out whether you have been exposed to a harmful substance and to measure how much of it may be present in your body, so your doctor can decide on the right follow-up care and treatment plan.
Your healthcare provider may order this test if you work with or are exposed to isocyanates, have symptoms like skin rashes, breathing difficulties, or unexplained allergic reactions. It can also help monitor long-term exposure risks.
Before the test, tell your doctor about any medications, vitamins, or supplements you take, as well as any recent illnesses or possible contact with harmful substances at home or at work. In most cases you can eat and drink normally beforehand, and your care team will explain exactly where to go and what will happen during your visit.
No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The process takes a few minutes, and you can resume normal activities afterward.
Your results show the level of the substance found in your blood. A normal level usually means no significant exposure, while a higher level may suggest recent or ongoing exposure. Your doctor will interpret your numbers along with your symptoms and medical history, and may order repeat testing to confirm the findings before recommending any treatment.
Results help determine if you’ve been exposed to harmful levels of isocyanates. High levels may indicate recent or ongoing exposure, which could affect your health over time.
Exposure often happens through contact with contaminated soil, dust, old paint, or tainted drinking water, as well as through certain jobs such as construction or manufacturing, hobbies like welding or pottery, and some foods, imported products, or traditional remedies that may contain harmful substances.
Exposure often occurs in industries like manufacturing, construction, or automotive repair where adhesives, paints, or sealants containing isocyanates are used. Occupational settings are the most common sources.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used for occupational health screening to identify potential risks from isocyanate exposure. Elevated levels may prompt further evaluation for allergic reactions, respiratory conditions, or long-term health monitoring.
Short name
Isocyanate Exposure Test
Frequently asked questions
What triggers this test?
How long does it take to get results?
Can I fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy