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Isocyanate Exposure Measurement (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of isocyanates, a group of chemicals used in adhesives, coatings, and sealants, which can cause health issues if inhaled or absorbed through the skin.

Quick summary

["Isocyanates may pose risks to lung and skin health; this test helps assess potential exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17028-2
Short code
Isocyanate IgM Qn
Synonyms
Isocyanate IgM Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test For?

Isocyanates are industrial chemicals that can enter your body through inhalation, skin contact, or ingestion. High exposure may lead to respiratory irritation, skin allergies, or long-term health effects like lung disease. This test helps doctors evaluate if your exposure is within safe limits or if further action is needed.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is processed to separate serum or plasma, which is then tested for isocyanate presence using a specialized immunoassay or similar method. Results are compared to reference ranges for your age and health status.

What Does the Result Mean?

Results may indicate whether your exposure to isocyanates is elevated. Very high levels could suggest recent or prolonged exposure, while normal levels suggest no significant risk. Your healthcare provider will interpret results in the context of your medical history and symptoms.

Common Causes of Abnormal Results

Abnormally high levels may occur in workers exposed to isocyanates in manufacturing, construction, or cleaning industries. Environmental exposure from household products (e.g., paints, glues) can also lead to elevated readings. Symptoms like coughing, skin rashes, or breathing difficulties may accompany abnormal results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Isocyanate Level

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you work in an industry with isocyanate exposure, have symptoms like persistent coughing, skin irritation, or breathing difficulties, or if you’ve been exposed to industrial chemicals. It helps assess potential health risks and guide protective measures.
What should I do if my test result is high?
If your result is elevated, follow your doctor’s advice for reducing exposure (e.g., wearing protective gear, avoiding certain products). They may recommend further testing, adjustments to your work environment, or monitoring for long-term effects.
How often should I get this test?
Frequency depends on your exposure risk. Workers in high-risk jobs may need regular testing; others may only need it if symptoms arise or during follow-up for known exposure. Always ask your doctor for personalized guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy