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Isosorbide Mononitrate (Serum or Plasma Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of isosorbide mononitrate, a medication used to help manage chest pain (angina) caused by reduced blood flow to the heart. It helps doctors assess whether your medication levels are within the expected range for effectiveness and safety.

Quick summary

["This test helps ensure your medication is working properly and avoids potential side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73324-6
Short code
Isosorbide ind plt IgM SerPl Ql FC
Synonyms
Isosorbide ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking isosorbide mononitrate to treat angina and want to check if your blood levels are appropriate. It may also be done during monitoring for side effects or to adjust your dosage.

What Does This Test Measure?

The test measures the concentration of isosorbide mononitrate in your blood (either serum or plasma). This helps determine if the medication is present at levels that are likely to provide relief from angina symptoms without causing harmful effects.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm, by a healthcare professional. The blood is then processed to separate the serum or plasma for testing.

What Are Common Reasons for Testing?

Common reasons include evaluating whether the medication is working as intended, checking for toxicity (unusually high levels), or adjusting your dose if symptoms persist or change.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for managing angina treatment by ensuring therapeutic drug levels. Low levels may indicate insufficient medication, while high levels could signal potential side effects like headaches or dizziness. Regular monitoring helps balance effectiveness and safety.

Short name

Isosorbide Mononitrate Level

Frequently asked questions

What does a high or low result mean?
A high result may suggest your body is metabolizing the medication too quickly or you may need a different medication. A low result could mean your current dose isn’t enough to control symptoms. Your doctor will interpret results in the context of your symptoms and other health factors.
How often should I get this test?
Your doctor will determine the frequency based on your treatment plan, medication regimen, and overall health. Typically, tests may be done periodically (e.g., every few months) to monitor levels, especially if you’re on long-term medication.
Can lifestyle changes affect this test result?
Yes, certain lifestyle factors like diet, exercise, and stress can influence medication absorption and metabolism. Avoiding certain foods (e.g., those high in nitrates) or smoking may help maintain stable levels. Always discuss lifestyle adjustments with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy