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Immunoassay for Retinoic Acid (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of retinoic acid, a form of vitamin A, in your blood. It may be used to monitor your response to isotretinoin treatment or assess metabolic health.

Quick summary

["This test helps track vitamin A metabolism and response to isotretinoin therapy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73322-0
Short code
ISOtretinoin ind plt IgM SerPl Ql FC
Synonyms
ISOtretinoin ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking isotretinoin (a medication used to treat severe acne or other skin conditions) to ensure it’s working properly or to check for potential side effects related to vitamin A metabolism. It may also be used in research or specialized clinical settings to evaluate metabolic pathways.

What Does the Test Measure?

Retinoic acid is a biologically active form of vitamin A that plays a role in skin health, immune function, and cell growth. Elevated or low levels may indicate how well your body is processing isotretinoin or suggest underlying metabolic issues.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it is analyzed using an immunoassay method to detect retinoic acid levels. No special preparation is needed, but fasting may be advised depending on clinical context.

What Are Possible Results?

Results are reported as a concentration of retinoic acid in the blood (typically in ng/mL or similar units). Interpretation depends on clinical context, such as your treatment regimen or symptoms. Your provider will discuss findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test may be particularly relevant for patients on isotretinoin to monitor vitamin A toxicity risks (e.g., liver function, bone health) or assess therapeutic efficacy. Abnormal levels could signal metabolic disturbances or drug interactions, prompting further evaluation.

Short name

Retinoic Acid Level

Frequently asked questions

Will I need to prepare for this test?
No specific preparation is required, but your provider may advise fasting or avoiding certain medications. Always follow their instructions for best accuracy.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your provider will contact you once they’re ready.
Can I fast before this test?
Fasting may not be required, but your provider may recommend it if this test is part of a broader metabolic evaluation. Ask your healthcare team for clarity.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy