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Itraconazole, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of itraconazole in blood to help confirm that an antifungal medication is being absorbed and used safely.

Quick summary

["This blood test helps determine whether your itraconazole dose is providing an appropriate drug level."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40583-7
Short code
ITA SerPl-mCnc
Synonyms
ITA SerPl-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of itraconazole, a prescription antifungal medicine, in your blood. Your clinician uses the result to help assess drug absorption, dosing, and the risk of side effects.

Why might I need this test?

The test may be ordered when you are taking itraconazole for a fungal infection, especially when treatment is not working as expected or you have conditions or medicines that may affect drug absorption. It can also help monitor people who take itraconazole long term.

How is the test performed?

A blood sample is collected and sent to a laboratory, where the itraconazole concentration is measured. The result is reported as an amount of drug per unit volume of blood.

How do I prepare for the test?

Take itraconazole exactly as prescribed. Because blood levels depend on dosing and absorption, your clinician may ask you to have the blood drawn at a specific time relative to your doses. Do not stop the medicine unless your clinician instructs you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Itraconazole level

Frequently asked questions

What does an itraconazole blood level measure?
It measures how much itraconazole is present in your blood at the time of the blood draw. This helps your clinician judge whether absorption and dosing are appropriate.
Why might my itraconazole level be low?
A low level can result from not taking the medicine as directed, taking it incorrectly, poor absorption, or interactions that reduce its availability. Your clinician will review these possibilities.
Are there risks from having too much itraconazole?
High levels can increase the risk of side effects, including effects on the heart, liver, or other organs. Your clinician will interpret the level along with your symptoms and other medications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy