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Ita Index (Cerebrospinal Fluid)

Published: August 9, 2026Updated: August 16, 2026

This test measures a calculated ratio of protein components in your cerebrospinal fluid (CSF) to help assess inflammation or infection in the central nervous system.

Quick summary

["Helps evaluate possible brain or spinal cord inflammation or infection by analyzing protein patterns in CSF."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104478-3
Short code
ITpA-Index Ser+CSF
Synonyms
ITpA-Index Ser+CSF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is the CSF Inflammatory Index Used For?

Doctors may use this test to diagnose conditions like meningitis, encephalitis, or other inflammatory diseases affecting the brain or spinal cord. It helps differentiate between infections, autoimmune responses, or other causes of altered CSF protein levels.

How Is the CSF Inflammatory Index Performed?

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). The sample is then analyzed in a lab to calculate the ratio of specific protein markers, which may include albumin, globulins, or other proteins.

Why Might You Need This Test?

You might need this test if you have symptoms like severe headaches, neck stiffness, fever, confusion, or neurological issues that suggest inflammation or infection in the central nervous system. Your doctor may also order it if you have a history of conditions like multiple sclerosis, lupus, or other autoimmune diseases.

What Are Common Causes?

Common causes include bacterial or viral infections (e.g., meningitis), autoimmune diseases (e.g., multiple sclerosis, Guillain-Barré syndrome), or conditions like subarachnoid hemorrhage. Elevated results may also indicate chronic inflammation or certain cancers affecting the CNS.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Inflammatory Index

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Is there any preparation needed before the test?
No special preparation is required, but you may need to avoid certain medications (like blood thinners) or stay hydrated, depending on your doctor’s instructions. Avoid caffeine or alcohol before the procedure.
Can this test replace other diagnostic tests?
No, this test is often used alongside other tests (like MRI, blood cultures, or lumbar puncture analysis) to provide a more complete picture. Your doctor will interpret results in the context of your symptoms and medical history.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy