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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61251-5
Short code
Japanese Cedar IgE/IgE total %
Synonyms
Japanese Cedar IgE/IgE total %
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens like pollen, dust mites, or certain foods. While IgE is normal in small amounts, higher levels may suggest allergies or other immune conditions.

Why Might You Need This Test?

Doctors may order this test to diagnose allergies, check for allergic reactions, evaluate immune system function, or monitor conditions like asthma or chronic urticaria.

How Is the Test Done?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure IgE levels using a sensitive immunoassay method.

What Do Results Mean?

Results are compared to reference ranges, but exact values depend on the lab. Elevated IgE levels may indicate allergies, while very high levels could signal conditions like atopic dermatitis or parasitic infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgE levels can indicate an overactive immune response to allergens or other triggers. High IgE is often linked to allergic diseases, but it can also appear in conditions like certain autoimmune disorders or infections.

Short name

IgE Total

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are most commonly linked to allergies (e.g., hay fever, food allergies) or atopic conditions (e.g., asthma, eczema). Other possible causes include parasitic infections or certain immune disorders.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on the lab and testing process.
Can I take anything before the test?
No special preparation is needed, but inform your doctor about any medications, especially antihistamines, which may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy