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Serum or plasma concentration of total protein (substance concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein status and kidney function.

Quick summary

["Total protein levels can signal kidney issues or nutritional deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110912-3
Short code
JCPyV DNA Msmt CSF
Synonyms
JCPyV DNA Msmt CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Is Total Protein Used For?

Total protein testing is often used to evaluate kidney function, detect kidney disease, or assess nutritional health. It can also help identify conditions like liver disease or dehydration.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The protein level is measured from either serum (liquid after blood clotting) or plasma (liquid portion after blood is centrifuged).

What Might Affect Results?

Factors like diet (high-protein vs. low-protein foods), kidney disease, liver disease, dehydration, or certain medications can influence protein levels. Recent blood loss or severe illness may also impact results.

When Might You Need This Test?

Your doctor may order this test if you have symptoms like swelling, weight changes, fatigue, or if they suspect kidney, liver, or nutritional issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

Why do I need to fast before this test?
Fasting is not typically required for total protein testing, as it measures protein levels in your blood regardless of what you ate. However, your doctor may specify instructions based on your specific situation.
How long will it take to get my results?
Results are usually available within 1 to 3 business days, depending on your lab and healthcare provider’s process.
Can I take anything for this test?
No special preparations are needed, but avoid heavy meals or certain medications that might affect protein levels if instructed by your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy