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Serum or Plasma Immunoassay for Anti-Cardiolipin Antibodies (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies in your blood that target cardiolipin, a fatty substance found in cell membranes. These antibodies may indicate an autoimmune condition or increased risk for certain blood clots.

Quick summary

["This test helps assess potential autoimmune activity or blood clot risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109814-4
Short code
JCV IgM Msmt CSF
Synonyms
JCV IgM Msmt CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Cardiolipin antibodies are part of a broader group of autoimmune markers. They can be detected in conditions like lupus, antiphospholipid syndrome, or other autoimmune disorders. The test specifically looks for IgG antibodies, which are one type of antibody your immune system produces to fight infections.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of autoimmune diseases, such as unexplained fatigue, joint pain, or a history of blood clots. It may also be used to monitor conditions like lupus or antiphospholipid syndrome.

What to Expect Before the Test

No special preparation is usually needed. You may have a blood sample drawn from a vein in your arm. If you are on blood thinners, inform your doctor before the test.

What Are Possible Results?

Results are qualitative (positive or negative) and do not provide a specific numeric range. Elevated levels may suggest an autoimmune response, but they are not definitive on their own. Results should be interpreted by your healthcare provider in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-Cardiolipin Antibodies (IgG)

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains antibodies targeting cardiolipin. This may indicate an autoimmune process, but it doesn’t diagnose a specific condition alone. Your doctor will consider your symptoms, medical history, and possibly other tests to determine next steps.
Can this test be used to diagnose lupus?
No, this test alone cannot diagnose lupus. It is one of many possible markers that may be checked. Lupus diagnosis typically involves a combination of clinical findings, other blood tests, and sometimes skin or kidney tests.
Are there any risks or side effects from this blood test?
The most common side effect is a slight bruise or soreness at the needle insertion site. Rarely, there may be mild swelling or pain. Most people experience no serious complications from this simple blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy