Total Protein in Serum (Mass Concentration)
This test measures the total amount of protein in your blood serum, which includes important proteins like albumin and globulins that help maintain fluid balance, support immunity, and transport nutrients.
["Your blood protein levels can signal health issues like malnutrition, kidney disease, or liver problems."]
Key facts at a glance
- LOINC
- 39091-4
- Short code
- Johnson grass IgE/IgE total %
- Synonyms
- Johnson grass IgE/IgE total %
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why It Matters in Your Health
Blood proteins play several critical roles in your body. Albumin helps keep fluids in your blood vessels, preventing swelling, and supports the transport of fats and hormones. Globulins, which include antibodies, assist in fighting infections and inflammation. Abnormal levels can indicate conditions like dehydration, liver disease, or chronic kidney disease.
What Can Affect Your Results?
Several factors may influence your total protein test results, including recent meals (especially high-protein foods), certain medications (like steroids or diuretics), dehydration or overhydration, and underlying health conditions like kidney disease or liver disorders.
Common Conditions Monitored
Healthcare providers often check total protein levels to diagnose or monitor conditions such as malnutrition, chronic kidney disease, liver disease (like cirrhosis), and certain autoimmune disorders. It can also help assess the effectiveness of treatments for these conditions.
What to Expect During the Test
This test is typically done by drawing a small amount of blood from a vein in your arm. The blood sample is sent to a lab, where it is processed to separate serum (the liquid part after clotting). The protein content is then measured using specialized laboratory techniques.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance of Total Protein Levels
Short name
Total Protein
Frequently asked questions
What does my total protein test result mean?
How often should I get this test?
Can I prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy