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Serum/plasma substance concentration (bromocresol green dye-binding protein)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a specific protein in your blood, which can help assess liver function and protein synthesis.

Quick summary

["This test helps evaluate liver health and protein metabolism by tracking dye-protein interactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101096-6
Short code
Jo sup(a) Ab SerPl Ql
Synonyms
Jo sup(a) Ab SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses bromocresol green dye, a chemical that binds to certain proteins in your blood. When the dye binds, it changes color, allowing the lab to measure how much dye is bound to these proteins. This helps determine the concentration of these proteins, which can reflect liver function and overall protein levels in your body.

Why It Matters in Medicine

This test is less commonly used today but historically helped diagnose liver disease or conditions affecting protein production. Modern tests often replace it with more specific measures of liver function.

Common Uses and Indications

This test may be used in rare cases to assess liver function or protein abnormalities, particularly when other tests are inconclusive or when historical data is needed.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is then processed to separate serum or plasma, which is sent to the lab for testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

While less frequently performed today, this test can provide insights into liver disease, protein synthesis disorders, or malnutrition by measuring specific protein binding capacity. Abnormal results may indicate conditions like cirrhosis, liver failure, or severe protein deficiencies.

Short name

BCG Protein Binding Assay

Frequently asked questions

What causes abnormal results in this test?
Abnormal results may occur due to liver disease (e.g., cirrhosis, hepatitis), severe protein malnutrition, or conditions affecting protein synthesis. Always discuss findings with your healthcare provider.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times.
Is this test painful?
The blood draw may cause mild discomfort, but it is generally quick and well-tolerated. Most people experience minimal pain afterward.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy