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Serum or plasma concentration of protein (e.g., albumin, globulin, or total protein)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein levels and identify potential issues like malnutrition, kidney problems, or liver disease.

Quick summary

["Your blood protein levels can signal underlying health concerns that need attention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9879-8
Short code
J Pnt Depr L-AVR
Synonyms
J Pnt Depr L-AVR
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to check for conditions affecting protein synthesis, breakdown, or retention in the body. It’s often used alongside other blood tests to diagnose or monitor diseases like kidney disease, liver disease, or malnutrition.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. Wear comfortable clothing and plan to stay near a testing facility for a short time.

What Happens During the Test?

A healthcare provider will insert a needle into a vein in your arm to collect a blood sample. You may feel a brief pinch, but the procedure is quick and typically painless. The blood is then sent to a lab for analysis.

What Are Common Results and Their Meanings?

Results can vary based on the specific protein measured (e.g., albumin, globulin, or total protein). Low levels may indicate malnutrition, kidney or liver disease, or excessive protein loss. High levels could suggest dehydration, inflammation, or certain medical conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What does a low total protein level mean?
Can diet affect my protein test results?
High protein levels can result from dehydration, inflammation, or certain medical conditions. In some cases, it may reflect an overproduction of proteins. Your doctor will discuss your symptoms and other test results to understand the reason.
Yes, diet can influence protein levels. High-protein diets or certain medical conditions may temporarily alter results. If your doctor suspects diet-related changes, they may recommend fasting or specific dietary adjustments before retesting.
The frequency depends on your health status and symptoms. Your doctor may order this test periodically if you have conditions like kidney disease, liver disease, or malnutrition. Follow their guidance for scheduling follow-up tests.
How often should I get this test?
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy