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Serum or plasma concentration of dehydroepiandrosterone sulfate (DHEAS)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced by the adrenal glands that plays a role in sex hormone regulation.

Quick summary

["DHEAS helps assess adrenal function and can be useful in evaluating conditions related to hormone balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9884-8
Short code
J Pnt Depr L-V2
Synonyms
J Pnt Depr L-V2
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is DHEAS Used For?

DHEAS is commonly checked to evaluate adrenal gland health, especially in conditions like adrenal insufficiency, Cushing’s syndrome, or hyperandrogenism. It may also be used in fertility evaluations, hormone replacement therapy planning, or monitoring certain cancers that produce hormones.

Why Might You Need This Test?

Your healthcare provider may order a DHEAS test if you have symptoms like low energy, fatigue, or hormonal imbalances. It can also be part of routine screening for certain conditions or before certain treatments.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab for processing to measure DHEAS levels.

What Does a DHEAS Test Tell You?

Lower-than-expected DHEAS levels may indicate adrenal problems, while higher levels could suggest conditions like polycystic ovary syndrome (PCOS) or certain cancers. However, results should always be interpreted by a healthcare provider in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: DHEAS plays a key role in hormone metabolism and can reflect underlying adrenal or endocrine system dysfunction. Abnormal levels may signal conditions requiring further medical evaluation, such as adrenal insufficiency, hormonal imbalances, or metabolic disorders.

Short name

DHEAS

Frequently asked questions

What does a DHEAS test measure?
A DHEAS test measures the amount of dehydroepiandrosterone sulfate (a hormone precursor) in your blood, which helps assess adrenal gland function and hormone balance.
How long does it take to get DHEAS results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you.
Can diet or supplements affect DHEAS levels?
Yes, certain foods, supplements, or medications (like steroids) may influence DHEAS levels. Always inform your provider about any supplements or medications you’re taking before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy