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Substance concentration of a specific protein in serum/plasma (e.g., a marker for protein electrophoresis)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in your blood, which can help identify conditions affecting protein balance or detect abnormalities in protein structure.

Quick summary

["Protein electrophoresis helps diagnose conditions like multiple myeloma, liver disease, or kidney problems by revealing unusual protein patterns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
18560-3
Short code
J Pnt ST Amp+60ms L-II
Synonyms
J Pnt ST Amp+60ms L-II
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like unexplained weight loss, frequent infections, swelling, or signs of organ damage. It’s also used to monitor certain diseases or check for genetic disorders affecting protein production.

What to Expect Before the Test

No special preparation is needed, but you may fast for 8–12 hours before the draw if instructed. Bring any medications or supplements you’re taking to discuss with your provider.

How the Test Works

A small blood sample is taken from a vein in your arm. The blood is then separated into plasma or serum and analyzed using gel electrophoresis to separate proteins by size and charge.

What the Results Mean

Results show bands representing different protein types. Abnormal patterns (e.g., extra bands, missing bands, or unusual shapes) may indicate conditions like protein disorders, infections, or metabolic issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein electrophoresis can signal conditions such as monoclonal gammopathy (e.g., multiple myeloma), liver disease (e.g., cirrhosis), or hereditary protein disorders. It’s also used to monitor treatment responses in some cases.

Short name

Protein Electrophoresis Profile

Frequently asked questions

What causes abnormal protein electrophoresis results?
Abnormal results may be linked to conditions like multiple myeloma (excess abnormal proteins), liver or kidney disease (altered protein synthesis), or certain genetic disorders. Lifestyle factors (e.g., diet, medications) can also influence protein levels.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow up with your provider to discuss findings.
Can I eat or drink before this test?
Check with your provider first, but generally, fasting may be required for some protein tests. Avoid alcohol or certain medications that could interfere with results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy