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Hemoglobin A1c (HbA1c) with 24-Hour Urine Collection for Creatinine Clearance

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar over the past 2–3 months and evaluates how well your kidneys filter blood, using a urine sample.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
18565-2
Short code
J Pnt ST Amp+60ms L-V4
Synonyms
J Pnt ST Amp+60ms L-V4
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why HbA1c is Important for Diabetes Management

HbA1c reflects your blood sugar levels over time, giving doctors a clearer picture of how well your diabetes is controlled. It’s a key tool for adjusting treatments like insulin or medication.

How Urine Creatinine Clearance Works

This part of the test checks how efficiently your kidneys remove creatinine—a waste product from muscle breakdown—from your urine. It helps assess kidney function alongside your HbA1c results.

What to Expect Before Your Test

For HbA1c: No special prep is needed, but fasting isn’t required. For urine creatinine clearance: Collect all urine over 24 hours (start timing after your first morning pee). Drink enough fluids to produce about 600–800 mL/day.

Common Causes of Abnormal Results

High HbA1c may indicate poor diabetes control, while abnormal urine creatinine levels could signal kidney issues. Both may require follow-up with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: HbA1c and Kidney Function Together

Short name

HbA1c + Urine Creatinine Clearance

Frequently asked questions

Why do I need both tests together?
Your doctor combines these tests to assess diabetes management *and* kidney health. High blood sugar can damage kidneys over time, so monitoring both helps prevent complications.
Can diet affect these results?
HbA1c reflects long-term sugar levels, so diet changes take weeks to show effects. Urine creatinine clearance depends on fluid intake and kidney function, not diet directly.
What if my urine sample isn’t complete?
If you miss urine collection or have an incomplete sample, your lab may request a repeat. Always follow your provider’s instructions for accuracy.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy