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Carboxylated Vitamin K-dependent Protein C (Anticoagulant Protein C)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of carboxylated vitamin K-dependent protein C in your blood, an important protein that helps prevent blood clots from forming. It may be used to assess your risk for blood clotting disorders or monitor treatment for conditions like protein C deficiency.

Quick summary

Helps evaluate blood clotting risk and monitor protein C levels for clotting disorders.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78847-1
Short code
JWH-210 carboxypentyl CtO Ur Cfm-mCnc
Synonyms
JWH-210 carboxypentyl CtO Ur Cfm-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a history of blood clots, certain blood disorders, or if you’re taking medications that affect blood clotting. It could also be part of a broader evaluation for conditions like disseminated intravascular coagulation (DIC) or inherited clotting disorders.

How the Test Works

The test uses a blood sample to measure the amount of carboxylated protein C, a form of the protein that’s activated by vitamin K. The method typically involves a specialized immunoassay to detect and quantify this specific protein.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The sample is processed to separate plasma, where the protein C levels are measured. This test is usually done on fresh plasma to ensure accurate results.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to stop certain medications (like anticoagulants) for a short time if directed by your provider. Avoiding strenuous activity or eating heavy meals before the test can help ensure consistency in your blood sample.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low levels of carboxylated protein C can indicate a higher risk of blood clots, especially in people with inherited or acquired clotting disorders. It may also help diagnose or monitor conditions like protein C deficiency, liver disease, or certain types of autoimmune disorders. High levels might be seen in some inflammatory or infectious conditions, though this is less common.

Short name

Protein C (Carboxylated)

Frequently asked questions

What Does a Low or High Result Mean?
A result below normal may suggest an increased risk of clotting problems, particularly if combined with other risk factors like family history or lifestyle choices. Your provider will interpret results in the context of your overall health and medical history.
Does This Test Require Dietary Restrictions?
No specific dietary restrictions apply, but if you’re on blood-thinning medications, follow your provider’s instructions carefully. Avoiding alcohol or certain supplements (like vitamin K-rich foods) may be advised if your test is part of a monitoring plan.
How Often Should I Get This Test?
Frequency depends on your medical condition. If you have a clotting disorder, your provider may recommend regular monitoring. For general health checks or routine screening, this test is rarely done unless symptoms or risk factors suggest it.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy