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Carboxylated Vitamin K-Dependent Protein C (Protein C, Activated, Carboxylated)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of carboxylated vitamin K-dependent protein C in your blood, which helps assess your blood clotting ability and potential risk for clotting disorders.

Quick summary

["This test helps evaluate how well your blood can clot normally and may be used to monitor conditions affecting clotting factors."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72804-8
Short code
JWH-210 carboxypentyl Ur Cfm-mCnc
Synonyms
JWH-210 carboxypentyl Ur Cfm-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a history of blood clots, certain blood disorders, liver disease, or if you’re taking medications that affect blood clotting. It may also be used during pregnancy or before surgery to check for clotting risks.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw. Avoid taking vitamin K supplements for 5–7 days before testing, as they can affect results.

How the Test Works

A small sample of blood is drawn from a vein in your arm. The blood is then analyzed to measure the carboxylated form of protein C, which is essential for normal blood clotting function.

Possible Results and Interpretation

Results may indicate whether your blood clotting system is functioning properly or if there’s an increased risk of clotting or bleeding. Abnormal results could signal underlying conditions like protein C deficiency or liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Protein C (Activated, Carboxylated)

Frequently asked questions

What does a low level of carboxylated protein C mean?
A low level may suggest a genetic disorder (protein C deficiency), liver disease, or conditions that interfere with vitamin K production or blood clotting. Your provider will discuss next steps based on your overall health and symptoms.
What does a high level of carboxylated protein C mean?
High levels are less common but may occur with certain medications or rare genetic factors. Your provider will review your medical history and other test results to understand the cause.
Can diet affect this test?
Yes, high intake of vitamin K (found in leafy greens, some oils) can raise protein C levels. Avoiding vitamin K supplements for a few days before testing helps ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy