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Urine Creatinine-to-Creatinine Clearance Ratio (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter waste products from your blood over a 24-hour period using urine samples. It helps assess kidney function and blood flow to the kidneys.

Quick summary

["This test evaluates kidney efficiency by comparing urine waste to blood waste over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73917-7
Short code
JWH-250 4/5-OH-pentyl Ur Ql Cfm
Synonyms
JWH-250 4/5-OH-pentyl Ur Ql Cfm
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like frequent urination, swelling in your legs, high blood pressure, or if you have a history of kidney disease. It may also be used to check kidney function before certain surgeries or treatments.

How the Test Works

You’ll collect all urine for 24 hours in a special container. The test measures creatinine levels in both your urine and blood to calculate how well your kidneys remove waste from your bloodstream.

Sample Collection Process

Start collecting urine immediately after waking up (do not use the first morning urine). Empty your bladder, then collect every drop for 24 hours. Store urine in a cool place and return it to your lab on the same day. Avoid foods like red meat or caffeine that may affect results.

What to Expect Before the Test

No special preparation is needed, but drink plenty of water unless instructed otherwise. Avoid medications that may affect kidney function unless approved by your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low results may indicate poor kidney function or blockages in the urinary tract, while high results could suggest dehydration, high blood pressure, or conditions like diabetes. This test helps diagnose and monitor kidney disease, blood pressure issues, and other health problems affecting kidney function.

Short name

Urine Creatinine Clearance Ratio

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab. Follow-up with your doctor to discuss findings.
What causes abnormal results?
Abnormal results can be due to kidney disease, dehydration, high blood pressure, diabetes, or urinary tract blockages. Your doctor will review your full medical history and other test results to determine the cause.
Can I drink alcohol before this test?
Alcohol may not affect this test directly, but it can impact overall health and kidney function. Avoid excessive alcohol use before testing unless advised by your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy