Carboxylated Vitamin K-dependent Protein C (Antithrombin III Coated, Mass Concentration)

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms of blood clotting disorders, such as deep vein thrombosis (DVT) or pulmonary embolism, or if you have conditions like liver disease that affect protein C production. It may also be used to monitor treatment for inherited or acquired clotting disorders.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for a few hours before the test, but always follow your provider’s instructions. Bring any medications you’re taking to your appointment.

How the Test Is Performed

A blood sample will be drawn from a vein, usually in your arm, by a healthcare professional. The sample is then processed to measure the mass concentration of carboxylated protein C.

What the Results Mean

Results are compared to standard reference ranges for healthy individuals. Low levels may indicate conditions like liver disease, protein C deficiency, or certain medications that interfere with protein synthesis. High levels are less common but may occur in certain genetic or metabolic disorders.