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Klebsiella pneumoniae DNA (Lower Respiratory Tract) – Nucleic Acid Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Klebsiella pneumoniae*, a type of bacteria that may cause infections in the lungs. It uses a specialized probe to identify the bacteria in a sample from your respiratory tract.

Quick summary

["This test helps diagnose lung infections caused by *Klebsiella pneumoniae* without needing a full culture."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94376-1
Short code
K. aerogenes DNA Lower resp Ql NAA+probe
Synonyms
K. aerogenes DNA Lower resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is done to help your doctor look for signs of an infection or another condition that may be affecting your health, so that the most appropriate treatment plan can be chosen for you based on accurate laboratory findings.

Your healthcare provider may order this test if you have symptoms like coughing up mucus, fever, or difficulty breathing, especially if you’ve been exposed to bacteria linked to lung infections. It’s particularly useful for patients with weakened immune systems or chronic lung conditions.

The test works by examining a small sample in a specialized laboratory, where trained technicians search for specific markers that can confirm or rule out the condition your doctor suspects, allowing your care team to make informed decisions.

A small sample of mucus or sputum from your lungs is collected and analyzed using a molecular probe. This probe binds to the DNA of *Klebsiella pneumoniae*, allowing the lab to detect its presence with high accuracy.

Your sample will be collected at the clinic or laboratory by a trained member of our staff, and the collection process usually takes only a few minutes, causes minimal discomfort, and is performed using sterile equipment for your safety.

You’ll likely cough into a sterile container or use a specialized swab to collect a sample. The sample is then sent to the lab for immediate analysis using nucleic acid amplification techniques.

Before the test, your doctor may give you simple instructions, such as whether you should avoid food, drink, or certain medications for a short period, so follow these directions closely and ask our staff if anything is unclear to you.

No special preparation is needed, but you may be asked to rinse your mouth with water before collecting the sample to avoid contamination. If you’re taking antibiotics, let your provider know, as this may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

This test provides a quick and reliable way to confirm a *Klebsiella pneumoniae* infection in the lungs, which can guide treatment decisions. It’s especially valuable for patients who cannot wait for traditional culture results or have severe symptoms.
How long will I need to wait before my test results are ready and my doctor can review them with me?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will discuss the findings with you during your follow-up visit.
Can I keep taking my antibiotics before getting this test, or should I stop them until after my sample has been collected?
Yes, but it’s important to inform your healthcare provider beforehand. Antibiotics may reduce bacterial presence, potentially altering the test results.
Insurance coverage depends on your plan and medical necessity. Check with your provider or insurance company to confirm if this test is included in your benefits.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy