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Escherichia coli (E. coli) DNA in Urine by Probe-Based Assay

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Escherichia coli* bacteria in your urine, which may help identify urinary tract infections (UTIs) caused by this specific type of bacteria.

Quick summary

["A positive result may indicate a UTI, but further testing is often needed to confirm the infection and guide treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61361-2
Short code
K. aerogenes DNA Spec Ql NAA+probe
Synonyms
K. aerogenes DNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent urination, pain or burning during urination, cloudy or strong-smelling urine, or fever—especially if you suspect a UTI. It can also be used to monitor certain conditions or guide treatment decisions in specific clinical scenarios.

How the Test Works

The test uses a specialized probe to detect fragments of *E. coli* DNA in your urine sample. This method is highly sensitive and can help differentiate between bacterial infections caused by *E. coli* and others.

Sample Collection and Preparation

You’ll provide a midstream urine sample (typically collected during urination). The sample is then analyzed in a lab to identify *E. coli* DNA. No special preparation is needed, but avoid urinating right before the test if possible.

What the Results Mean

A positive result suggests the presence of *E. coli* DNA, which may indicate a UTI. However, a negative result does not definitively rule out a UTI caused by other bacteria or non-bacterial causes. Results should always be interpreted by a healthcare provider in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

E. coli DNA Urine Test

Frequently asked questions

What does a positive result mean for my health?
A positive result strongly suggests *Escherichia coli* is likely the cause of your urinary symptoms. This bacterium is the most common cause of UTIs, so treatment with antibiotics targeting *E. coli* may be recommended. However, further testing (such as a urine culture) may still be needed to confirm the exact type of bacteria and guide treatment.
Could a negative result mean I don’t have a UTI?
Not necessarily. While a negative *E. coli* DNA test means no *E. coli* DNA was detected, other bacteria or non-bacterial causes (like irritation or inflammation) could still be responsible. Your healthcare provider may recommend additional tests or follow-up if symptoms persist.
How soon will I get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you and may recommend next steps, such as treatment or further testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy