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24-Hour Urinary Albumin-to-Creatinine Ratio (UACR)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of albumin, a protein, in your urine over 24 hours. It helps assess kidney function and detect early kidney damage, especially in people with diabetes or high blood pressure.

Quick summary

["Helps identify kidney problems early by checking protein loss in urine over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25682-6
Short code
Kappa LC 24h Ur-mRate
Synonyms
Kappa LC 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters for Kidney Health

Albumin is normally found in small amounts in urine, but if your kidneys are damaged, more albumin can leak into your urine. A 24-hour urine collection ensures you get an accurate picture of your protein loss, which can help doctors track kidney function over time.

How the Test Works

You’ll collect all your urine for a full 24-hour period, typically starting after you wake up. Your urine is then tested for albumin and creatinine levels. The ratio helps determine how much albumin is being lost relative to how much creatinine (a waste product from muscles) is present.

What to Expect Before the Test

No special preparation is needed, but you’ll need to keep track of all urine output in a container. Drink plenty of water to help flush your system, but avoid foods or medications that might affect urine protein levels (like certain supplements or high-sodium foods).

Common Causes of Abnormal Results

High albumin levels in urine may indicate kidney disease, diabetes, high blood pressure, or other conditions that damage kidney function. Low levels are usually normal, but repeated tests may be needed to confirm results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Albumin in urine (24-hour urine test)

Frequently asked questions

What does a high 24-hour urinary albumin-to-creatinine ratio mean?
A high ratio suggests your kidneys may be leaking albumin into your urine, which can be an early sign of kidney damage. This is often seen in people with diabetes, high blood pressure, or other kidney-related conditions. Your doctor may recommend further testing or adjustments to your treatment plan.
What does a low 24-hour urinary albumin-to-creatinine ratio mean?
A low ratio is generally normal and indicates that your kidneys are functioning well, with minimal protein loss in your urine. However, repeated tests are needed to rule out any temporary fluctuations in urine output or other factors.
Can diet affect this test?
Yes, certain foods, medications, or supplements (like high-sodium foods, NSAIDs, or some herbal products) can temporarily affect urine protein levels. Your doctor may ask you to avoid these for a few days before your test to get the most accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy