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Urine Albumin-to-Creatinine Ratio (UACR) or Urinary Albumin-to-Creatinine Ratio

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of albumin (a protein) to creatinine in your urine. It helps assess how much protein your kidneys are losing over time, often used to monitor kidney function and early signs of kidney disease.

Quick summary

["A simple urine test to check kidney health and protein loss."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111248-1
Short code
Kappa LC Msmt Ur
Synonyms
Kappa LC Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys normally filter waste and extra fluids from your blood. If they’re damaged, they may allow small amounts of protein (like albumin) to leak into your urine. This test helps detect early kidney problems, including diabetes-related kidney damage or high blood pressure effects.

How the Test Works

A small urine sample is collected (often in the morning). The albumin and creatinine levels are measured separately, then compared. The ratio helps identify protein loss relative to kidney function, even if kidney damage isn’t severe yet.

Preparation and Collection

No special preparation is needed. Collect a mid-stream urine sample (about 10–30 mL) in a clean container. If you’re using a 24-hour urine collection, follow your doctor’s instructions carefully to ensure accuracy.

What Results Mean

Higher-than-normal ratios may indicate kidney issues, especially in people with diabetes, high blood pressure, or a family history of kidney disease. Lower ratios suggest normal kidney function. Your doctor will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated UACR is a key marker for **microalbuminuria**, a stage of kidney disease where protein leaks into urine but kidney function may still be preserved. It’s often used alongside blood pressure and glucose tests to guide treatment for diabetes or hypertension. Early detection allows for interventions like blood pressure control or diabetes management to slow progression.

Short name

UACR

Frequently asked questions

How often should I get this test?
If you have diabetes or high blood pressure, your doctor may recommend this test every 1–3 years or more frequently if you’re at higher risk. For others without kidney concerns, it’s usually not routinely recommended unless symptoms (like swelling, fatigue) or risk factors appear.
What causes a high UACR result?
High UACR can result from kidney damage due to diabetes, high blood pressure, infections, or genetic conditions. It may also appear in people with obesity, certain medications, or autoimmune diseases. Always discuss symptoms or risk factors with your doctor to explore possible causes.
Can lifestyle changes affect UACR results?
Yes! Reducing salt intake, managing blood pressure and diabetes, staying hydrated, and maintaining a healthy weight may lower protein loss over time. Avoiding smoking and limiting alcohol can also support kidney health. Ask your doctor about personalized recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy