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Acetone in Whole Blood (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of acetone, a ketone body, in your blood. Ketones like acetone can build up when your body burns fat for energy, often seen in conditions like diabetes or starvation.

Quick summary

["Ketones in blood can signal metabolic changes that may require medical attention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53061-8
Short code
Ketones Bld-sCnc
Synonyms
Ketones Bld-sCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for elevated ketone levels, which can occur in conditions such as diabetic ketoacidosis, uncontrolled diabetes, or prolonged fasting. It may also be used to monitor metabolic health or assess dietary or lifestyle factors affecting energy production.

What Does a Positive Result Mean?

Elevated acetone levels may indicate your body is producing more ketones than usual. This can happen with certain medical conditions, dietary changes (like very low-carb diets), or in response to stress or illness. Always discuss results with your doctor to understand the cause and next steps.

What to Expect During the Test

This test involves drawing blood from a vein in your arm. You may feel a small pinch when the needle is inserted, but it usually only takes a few minutes. The blood sample is then sent to a lab for analysis.

Common Causes of Elevated Ketones

Ketones can rise due to factors like poorly managed diabetes, high-fat or low-carb diets, prolonged fasting, alcohol consumption, or certain illnesses (e.g., vomiting, dehydration). Stress or intense exercise can also temporarily increase ketone production.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

None

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and treatment plan. Your doctor may recommend testing more often if you have diabetes, are on a very low-carb diet, or are experiencing symptoms like nausea, fatigue, or unexplained weight loss.
What should I do if my ketone levels are high?
If your ketone levels are elevated, your doctor may advise adjustments to your diet, medication, or lifestyle. Seek immediate medical attention if you experience symptoms like confusion, rapid breathing, or severe vomiting, as these could signal a serious condition like diabetic ketoacidosis.
Can I eat or drink before this test?
Yes, you can eat and drink normally before the test unless your doctor instructs otherwise. However, if you’re fasting for another reason (e.g., for a different blood test), follow their guidance to avoid confusion in results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy