KIR2DS4 Full Variant Detection (Blood)
This test checks for the presence of specific genetic variants in the KIR2DS4 gene, which is part of the killer-cell immunoglobulin-like receptor (KIR) family. KIR genes influence immune responses, particularly in natural killer (NK) cells.
["Understanding your KIR2DS4 genetic profile may help assess immune function or inform certain medical decisions."]
Key facts at a glance
- LOINC
- 64423-7
- Short code
- KIR2DS4 full variant Bld/T Ql
- Synonyms
- KIR2DS4 full variant Bld/T Ql
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have a family history of immune-related conditions, are considering organ transplantation, or if you have a suspected genetic predisposition to certain diseases. It can also be part of research studies or genetic counseling evaluations.
What to Expect Before the Test
No special preparation is needed. A blood sample will be taken from a vein in your arm, similar to other blood tests. You may feel a slight pinch, but it usually doesn’t cause discomfort. The process takes about 5 minutes.
What the Test Results Mean
Results will indicate whether the KIR2DS4 gene variants are present in your DNA. These variants can influence how your immune system functions, particularly how NK cells respond to infections or tumors. Your healthcare provider will discuss the results in the context of your overall health and medical history.
Common Uses and Limitations
This test is primarily used for genetic research, immune function assessment, or as part of a broader genetic evaluation. It does not replace clinical diagnosis but can provide additional information for personalized medical care. Limitations include that results may not be directly applicable to everyone due to genetic diversity.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
KIR genes play a role in immune regulation, particularly in how NK cells recognize and respond to pathogens or abnormal cells. Variations in KIR2DS4 can affect immune responses, which may be relevant in conditions like autoimmune diseases, infections, or cancer. However, the clinical significance of these variants can vary widely among individuals and may require further interpretation by a healthcare provider or genetic counselor.
Short name
KIR2DS4 Genetic Test
Frequently asked questions
What does a positive result mean?
Can this test be used to diagnose a disease?
How long will it take to get my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy