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KIT Exon 13 Mutation Analysis, Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test looks for specific changes (mutations) in exon 13 of the KIT gene using a blood sample. It is used to help identify tumors that may respond to targeted therapy.

Quick summary

["A KIT exon 13 mutation result helps your care team understand whether certain targeted medicines may be useful."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87732-4
Short code
KIT Exon 13 Mut Anl Bld/T
Synonyms
KIT Exon 13 Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test examines a small section of the KIT gene called exon 13. The KIT gene makes a protein that helps control cell growth and division. Changes in this gene can cause cells to grow abnormally and are found in some cancers, including certain gastrointestinal stromal tumors (GISTs).

Why It May Be Ordered

Your doctor may order this test if you have a tumor known or suspected to be linked to KIT, such as a gastrointestinal stromal tumor. Knowing whether an exon 13 mutation is present can help guide treatment decisions, including whether medicines that target the KIT protein may be helpful.

How the Sample Is Collected

A blood sample is drawn from a vein, usually in your arm, and sent to a specialized laboratory. In some cases the test may be done on tumor tissue instead, so follow the instructions from your care team about which sample is needed.

What the Results Mean

A "mutation detected" result means a specific change in exon 13 of the KIT gene was found. A "not detected" result means that change was not seen. Your doctor will interpret the result together with your diagnosis, other test results, and your overall health. This test does not by itself diagnose or rule out cancer.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

KIT Exon 13 Mutation

Frequently asked questions

Does this test diagnose cancer?
No. It detects a specific gene change that may be present in certain tumors. Cancer diagnosis is based on multiple tests and clinical findings, so your doctor will interpret this result along with other information.
Will I need a tissue sample instead of blood?
It depends on your situation. This test can be performed on a blood sample, but some cases may require testing on tumor tissue. Your care team will tell you which sample type is appropriate.
Can a mutation be present even if the result says "not detected"?
The test looks for specific changes in exon 13 of the KIT gene. A "not detected" result means the tested change was not found, but it does not rule out other mutations in KIT or other genes. Discuss any questions about your results with your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy