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IgA Antibody to Hepatitis C Virus (IgA Anti-HCV)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies to the hepatitis C virus (HCV) in your blood, specifically targeting IgA antibodies. IgA antibodies are part of your immune system’s response to infections and can indicate an ongoing or past exposure to hepatitis C.

Quick summary

["This test helps determine if you may have been exposed to hepatitis C, even if you don’t yet have classic symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73745-2
Short code
KLH IgA Ser-mCnc
Synonyms
KLH IgA Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgA antibodies are a type of immune protein your body produces in response to hepatitis C virus infection. Detecting these antibodies can help identify whether you’ve been exposed to the virus, though they may not appear immediately after exposure. This test focuses on IgA specifically, which can sometimes be detected earlier or persist longer than other antibody types in some individuals.

Why Might You Need This Test?

Your healthcare provider may order this test if you have risk factors for hepatitis C, such as a history of blood transfusions before 1992, needle exposure, or chronic liver issues. It may also be used as part of screening or monitoring for hepatitis C in certain populations.

What Does a Positive Result Mean?

A positive result suggests you may have been exposed to hepatitis C virus and developed an immune response. However, it doesn’t confirm an active infection right away. Follow-up testing, such as HCV RNA testing, is often needed to determine if the virus is currently active in your body.

What Does a Negative Result Mean?

A negative result means your body did not detect IgA antibodies to hepatitis C at the time of testing. This could mean you have never been exposed or that your immune response hasn’t produced detectable IgA antibodies yet.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Your Results

Short name

IgA Anti-HCV

Frequently asked questions

How long will it take to get my results?
Test results are typically available within 1 to 3 business days, depending on your lab’s processing time. Follow-up instructions will be provided by your healthcare provider.
Can I get hepatitis C from this test?
No, this test involves only blood samples and does not pose a risk of transmitting hepatitis C or any other infection. Your blood is handled with strict safety protocols to prevent contamination.
Do I need to prepare for this test?
No special preparation is needed. You can eat, drink, or take medications as usual on the day of your test. However, inform your healthcare provider about any medications you’re taking, as some may affect test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy