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Pneumococcal Group DNA (Qualitative) in Nasopharyngeal Aspirate or Swab by Nucleic Acid Amplification Test

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Streptococcus pneumoniae* (pneumococcus), a common cause of pneumonia, ear infections, and other serious illnesses in children and adults.

Quick summary

["Helps identify if you may have an infection caused by pneumococcus before symptoms appear."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97624-1
Short code
K. pneumon group DNA Snv Ql NAA+non-prb
Synonyms
K. pneumon group DNA Snv Ql NAA+non-prb
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, cough, or trouble breathing, or if you’re at higher risk for pneumococcal infections (e.g., young children, elderly adults, or those with weakened immune systems). It can also be used to screen for colonization in people who may have been exposed to pneumococcus.

How the Test Works

A sample of your nasal secretions (nasopharyngeal aspirate or swab) is collected and tested for genetic material from pneumococcus using a specialized lab technique that detects DNA without measuring its quantity.

Sample Collection

A healthcare provider will gently insert a small swab into your nose to collect fluid from the back of your nasal passages. This is usually quick and painless, though it may cause a slight tickle or mild discomfort.

Test Results Interpretation

A positive result means genetic material from pneumococcus was found, suggesting possible infection. A negative result means no genetic material was detected, but this does not rule out infection entirely—other causes may be present.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Pneumococcal DNA Screen

Frequently asked questions

Can help confirm a diagnosis of pneumococcal infection early, allowing for prompt treatment with antibiotics to prevent complications or spread of the bacteria.
This test is not used to measure the severity of infection or guide dosage of antibiotics; it’s primarily for screening or confirming colonization.
If you have symptoms like severe coughing or difficulty breathing, additional tests (e.g., blood cultures or chest X-rays) may be needed to guide treatment.
This test is not a substitute for vaccination advice; if you’re eligible, discuss pneumococcal vaccination with your provider.
The test results may take 24–48 hours to return, depending on lab processing times.
No special preparation is needed, but avoid using nasal decongestants or sprays 24 hours before testing, as they may affect sample accuracy.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy