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Protein Electrophoresis (Serum) with Bromocresol Green (BCG) Dye

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood serum using electrophoresis with a bromocresol green dye. It helps identify abnormalities in protein levels that may indicate conditions like kidney disease, liver disorders, or other metabolic issues.

Quick summary

["This test helps diagnose and monitor conditions affecting protein balance in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106597-8
Short code
K pnm DNA Fld Ql NAA+n-prb
Synonyms
K pnm DNA Fld Ql NAA+n-prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates proteins in your blood based on size and charge, creating distinct bands. The bromocresol green dye binds to specific protein groups, allowing for qualitative assessment of albumin, globulins, and other fractions. This process helps detect shifts in protein composition that may signal underlying health concerns.

How the Test Works

Your blood is drawn and placed in a gel or medium. An electric current is applied, causing proteins to migrate toward the opposite charge. The BCG dye highlights different protein zones, which are then visually analyzed for relative concentrations.

Common Conditions Monitored

This test is often used to evaluate conditions like multiple myeloma, nephrotic syndrome, liver disease, or chronic kidney disease. Abnormal patterns may indicate excess or deficiency of certain proteins, guiding further medical evaluation.

When You Might Need This Test

Your healthcare provider may order this test if you have symptoms like unexplained weight loss, swelling, fatigue, or if they suspect conditions affecting protein metabolism. It’s also used as part of routine monitoring for certain chronic illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Protein Electrophoresis (BCG)

Frequently asked questions

Why might my doctor request this test?
Your doctor may order this test to investigate symptoms like unexplained swelling, changes in protein levels, or to monitor conditions affecting protein balance in your body.
What does it mean if my results show abnormal protein bands?
Abnormal bands may indicate conditions like multiple myeloma (excess monoclonal proteins), liver or kidney disease (altered albumin or globulin levels), or other metabolic disorders. Your doctor will discuss these findings with you and may recommend additional tests.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will contact you once they are ready to discuss the findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy