Immunoassay for Anti-Cardiolipin Antibodies (IgG and IgM) in Serum
This test measures the presence of antibodies in your blood that target cardiolipin, a fatty substance found in cell membranes. These antibodies may be linked to certain autoimmune conditions.
["Helps assess potential autoimmune or inflammatory risks, including lupus or other connective tissue disorders."]
Key facts at a glance
- LOINC
- 105663-9
- Short code
- K. variico sub tro DNA Spec Ql NAA+probe
- Synonyms
- K. variico sub tro DNA Spec Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects two types of antibodies—IgG and IgM—that target cardiolipin, a phospholipid commonly found in cell membranes. Elevated levels may suggest an autoimmune response, though they are not definitive for any specific condition.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms of autoimmune diseases (e.g., joint pain, fatigue) or if you’ve been diagnosed with conditions like lupus, rheumatoid arthritis, or other connective tissue disorders.
What Could Abnormal Results Mean?
High antibody levels may indicate an autoimmune response, but they are not alone enough to diagnose a condition. They can be part of a broader evaluation, including other blood tests and clinical assessments.
Common Conditions Linked to Elevated Levels
While not diagnostic, elevated anti-cardiolipin antibodies are sometimes associated with autoimmune diseases like systemic lupus erythematosus (SLE), antiphospholipid syndrome, or other inflammatory conditions. They may also appear in people without symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is often used as part of a broader evaluation for autoimmune disorders, particularly when other symptoms or test results suggest inflammation or immune system dysfunction. It can help monitor disease activity or assess risk in patients with suspected connective tissue diseases.
Short name
Anti-Cardiolipin Antibodies (IgG/IgM)
Frequently asked questions
Why do some people have high anti-cardiolipin antibodies without symptoms?
Can this test predict future health problems?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy