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Liver Function Panel with Alpha-1 Antitrypsin Measurement (Screening and Confirmatory)

Published: August 9, 2026Updated: August 16, 2026

This test checks key liver function markers and measures Alpha-1 Antitrypsin, a protein that helps protect lung and liver tissues from damage.

Quick summary

["Assesses liver health and genetic risk for conditions like emphysema or chronic liver disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75514-0
Short code
LA 2 screen W Reflex-Imp
Synonyms
LA 2 screen W Reflex-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test includes standard liver function tests (LFTs) such as bilirubin, albumin, alkaline phosphatase, and transaminases (ALT and AST), which help evaluate liver function and detect damage. It also measures Alpha-1 Antitrypsin (A1AT), a protein that can be low in genetic disorders affecting the lungs or liver.

Why It’s Ordered

Your doctor may order this test if you have symptoms like fatigue, jaundice, or unexplained liver issues, or if you have a family history of liver disease or lung conditions like alpha-1 antitrypsin deficiency.

Preparation and Specimen

No special preparation is needed. Blood is drawn from a vein, typically in your arm. If you’re taking blood thinners, let your doctor know to avoid bleeding risks.

What to Expect After Testing

Results may take a few days to a week to process. You’ll receive them directly from your healthcare provider, who will explain any findings and next steps.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Liver Function + Alpha-1 Antitrypsin

Frequently asked questions

Abnormal liver enzymes may indicate inflammation, infection, or damage, while low Alpha-1 Antitrypsin could signal genetic disorders requiring further testing or treatment options.
This test helps identify early signs of liver disease or genetic conditions that may need monitoring or intervention.
How long does it take to get results?
Results typically take between 1 to 7 days, depending on lab processing times and your healthcare provider’s workflow.
Can I eat or drink before this test?
No special diet is required, but avoid alcohol for 24 hours before the test if possible, as it may affect liver enzyme levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy