End-Stage Renal Disease (ESRD) Comprehensive Assessment Panel (2728)
This test evaluates key biomarkers to assess kidney function and identify signs of end-stage renal disease (ESRD), a severe condition where kidneys fail to properly filter waste and excess fluids from your blood.
ESRD assessment helps monitor kidney health and guide treatment decisions.
Key facts at a glance
- LOINC
- 68996-8
- Short code
- LABORATORYENDSTAGERENALDISEASEFORM2728
- Synonyms
- —
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
This panel typically includes tests for substances that reflect kidney function, fluid balance, and metabolic health. Common components may include electrolytes (e.g., sodium, potassium), creatinine, blood urea nitrogen (BUN), and markers like calcium, phosphorus, or parathyroid hormone (PTH). Some tests may also measure proteinuria or other indicators of kidney damage or dysfunction in urine samples.
Why It Matters for ESRD
Kidneys play a critical role in maintaining balance of essential substances in your body. When kidneys fail, harmful waste builds up, leading to serious health risks. This panel helps doctors track how well your kidneys are working and whether you need additional support like dialysis or medication.
Sample Collection and Preparation
Blood samples are usually drawn from a vein in your arm. Urine samples may also be collected depending on the specific tests included. Your healthcare provider will explain the process and ensure you’re comfortable. Avoid certain foods or medications before testing if instructed.
Common Tests Included
The exact tests vary, but may include: - Electrolytes (e.g., sodium, potassium) - Kidney function markers (e.g., creatinine, blood urea nitrogen) - Metabolic indicators (e.g., calcium, phosphorus) - Hormones like parathyroid hormone (PTH) - Protein in urine (proteinuria) to detect kidney damage.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
ESRD Panel
Frequently asked questions
This panel helps diagnose ESRD by identifying abnormal levels of substances that kidneys normally regulate. Elevated creatinine or BUN levels, for example, suggest impaired kidney function. Tracking these markers over time can help doctors adjust treatments to prevent complications like high blood pressure, bone disease, or fluid overload.
You may need this test if you have chronic kidney disease (CKD), diabetes, high blood pressure, or a history of kidney problems. Your doctor might also recommend it if you’re experiencing symptoms like swelling, fatigue, or frequent urination.
Your results will be compared to standard ranges. If levels are outside normal limits, it may indicate kidney dysfunction or ESRD. Your doctor will discuss these findings with you and explain next steps, such as lifestyle changes, medications, or further testing.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy