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Albumin and Total Immunoglobulin Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood levels of albumin and total immunoglobulins (antibodies), which help your body fight infections and maintain fluid balance.

Quick summary

["Albumin and immunoglobulins support immunity and fluid regulation in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57991-2
Short code
Lactalb IgE/IgE total %
Synonyms
Lactalb IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Albumin Measures

Albumin is a protein produced by your liver that helps keep fluids in your blood vessels and supports immune function. Low levels may indicate liver disease, kidney problems, or severe infections.

What Immunoglobulins Measure

Immunoglobulins (antibodies) are proteins that protect your body from infections. They include different types like IgG, IgA, and IgM, each playing a role in immune defense. Low levels may suggest weakened immunity or autoimmune conditions.

Why This Test Might Be Ordered

Your doctor may order this test to check for liver disease, kidney issues, malnutrition, or immune system problems. It can also help diagnose conditions like chronic kidney disease, liver cirrhosis, or infections.

Common Conditions Affecting Results

Low albumin or immunoglobulins might be linked to liver disease, kidney failure, malnutrition, or certain infections. High levels could rarely indicate overproduction of antibodies or certain blood disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Albumin/Ig Profile

Frequently asked questions

What does a low or high result mean for my health?
A low result may indicate conditions like liver disease, malnutrition, or kidney problems, while a high result is less common but could suggest certain immune disorders. Your doctor will discuss findings in the context of your medical history.
How often should I get this test?
Frequency depends on your health status. Your doctor will determine if regular testing is needed, especially if you have conditions like liver disease or immune disorders.
Can diet or lifestyle affect these test results?
Yes, diet (especially protein intake) and certain medications can influence albumin levels. Immunoglobulin levels are less affected by diet but may change with infections or immune responses. Always discuss lifestyle factors with your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy