Lactoferrin (Serum or Plasma)

What Is Lactoferrin?

Lactoferrin is a glycoprotein produced primarily by cells in the immune system, including white blood cells and certain epithelial cells. It binds iron to help control its availability and supports immune responses by neutralizing bacteria and viruses. In blood, it appears in both serum and plasma, though its concentration can vary based on health and immune activity.

Why Might You Need This Test?

Doctors may order lactoferrin testing to evaluate immune function, especially in conditions like chronic infections, inflammatory diseases, or certain cancers. It can also be part of broader assessments for malnutrition or iron metabolism disorders.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in the arm. The sample is then processed to separate serum or plasma for analysis using an immunoassay method, which detects the protein’s presence and concentration.

What Are Common Uses?

This test is less commonly used than others but may be considered in specific clinical scenarios, such as monitoring immune response in patients with chronic infections (e.g., tuberculosis, HIV), evaluating inflammatory conditions, or assessing nutritional status in certain populations.