Lactate in Serum/Plasma Measured by High-Performance Liquid Chromatography (2-Hour Postprandial)
This test measures the amount of lactate in your blood 2 hours after eating. Lactate is a byproduct of energy metabolism and can help assess how well your body handles glucose (sugar) after consuming food.
["Helps evaluate how your body processes sugar and energy after eating."]
Key facts at a glance
- LOINC
- 40284-2
- Short code
- Lactose 2h p Lac PO SerPl-sCnc
- Synonyms
- Lactose 2h p Lac PO SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 20
- Ref high
- 400
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82670
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, dizziness, or unusual sweating after meals, or if you have conditions like diabetes, metabolic disorders, or unexplained low blood sugar (hypoglycemia). It can also be used to monitor how well certain medications or treatments affect your blood sugar levels.
What to Expect Before the Test
You’ll likely fast for a few hours before the test, but the 2-hour postprandial part means you’ll eat a standard meal or snack before coming in. Bring a list of any medications you’re taking, as some may affect results. The blood draw is quick and done in a clinic or lab.
What the Test Results Mean
Lactate levels can vary based on your activity, diet, and overall health. High levels might suggest poor glucose tolerance, certain metabolic diseases, or conditions affecting how your body uses oxygen. Low levels could indicate severe illness or dehydration. Always discuss results with your provider.
Common Conditions Monitored
This test is often used to diagnose or monitor conditions like lactic acidosis (a serious buildup of lactate), mitochondrial disorders, or metabolic syndromes. It can also help assess how well you’re managing diabetes or other blood sugar-related issues.
Reference range
Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: Elevated lactate levels after eating may indicate impaired glucose metabolism, while persistently low levels can signal systemic stress or illness. This test is critical for diagnosing metabolic disorders and guiding treatment plans.
Short name
2-Hour Lactate Level (Post-Meal)
Frequently asked questions
What triggers a lactate test?
How long does it take to get results?
Can I eat or drink before the 2-hour postprandial part?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy