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Lipoprotein(a) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-like particle that carries both cholesterol and a protein called apolipoprotein(a). It may help assess your risk for heart disease.

Quick summary

["Lipoprotein(a) can contribute to artery-clogging plaque and may increase heart disease risk over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79973-4
Short code
LA ES area A2C
Synonyms
LA ES area A2C
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-d-a-c-measured-by-planimetry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Lipoprotein(a) is a unique lipoprotein that combines cholesterol with apolipoprotein(a). While it shares some traits with other cholesterol particles, it behaves differently in the body. This test specifically quantifies the total concentration of lipoprotein(a) particles, which may influence cardiovascular health beyond traditional cholesterol measures.

Why Might You Need This Test?

Doctors may order lipoprotein(a) testing if you have a family history of heart disease, high cholesterol, or other risk factors. It can also be part of a broader evaluation for conditions like aortic stenosis or certain genetic disorders. Some guidelines recommend screening for people with no symptoms but elevated risk factors.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed using a specialized immunoassay method to measure lipoprotein(a) concentration. Results are typically available within 1–3 business days.

What Are Common Results and Next Steps?

Results are reported as a numerical value representing lipoprotein(a) concentration in milligrams per deciliter (mg/dL). A high level may indicate increased risk for heart disease, but interpretation depends on your overall health profile. Your healthcare provider will discuss results and recommend next steps, such as lifestyle changes or further testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lp(a) Level

Frequently asked questions

How often will I need this test?
Lipoprotein(a) testing is not routinely recommended for everyone. Your doctor may suggest it if you have specific risk factors, such as a family history of heart disease, high cholesterol, or other cardiovascular conditions. Some guidelines suggest screening every 5–10 years for adults with moderate risk, but this varies by individual health status.
What does a high lipoprotein(a) level mean for my health?
A high lipoprotein(a) level may increase your risk of developing heart disease or having a heart attack, especially if combined with other risk factors like smoking, high blood pressure, or diabetes. It does not replace other cholesterol tests like LDL or HDL, but it provides additional insight into your cardiovascular risk profile.
Can lifestyle changes lower lipoprotein(a) levels?
While lifestyle changes like diet, exercise, and smoking cessation can help manage other risk factors, lipoprotein(a) levels are primarily influenced by genetics. Some studies suggest that certain medications (like statins) may have a modest effect, but there is no proven way to significantly lower lipoprotein(a) through diet or exercise alone.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy