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Lactate Dehydrogenase (LDH) Activity in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity level of the enzyme lactate dehydrogenase (LDH), which plays a role in energy production in cells. It can help identify conditions affecting cell damage or disease processes.

Quick summary

["LDH helps detect tissue damage or disease by measuring enzyme levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95127-7
Short code
LAM Ag Ur Ql IA.rapid
Synonyms
LAM Ag Ur Ql IA.rapid
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order LDH testing to investigate symptoms like fatigue, muscle weakness, or unexplained pain, which could signal conditions such as heart disease, liver problems, muscle injuries, or certain cancers. It’s also used in monitoring conditions like anemia, infections, or metabolic disorders.

What Does a High or Low LDH Level Mean?

Elevated LDH levels may indicate damage to cells in organs like the heart, liver, kidneys, or muscles. Low levels are less common but could suggest certain blood disorders or severe infections. Results are interpreted in relation to your overall health and symptoms.

Common Conditions Linked to LDH Levels

High LDH is often seen in conditions like myocardial infarction (heart attack), liver disease, hemolytic anemia (red blood cell breakdown), or certain cancers. It can also appear in muscle injuries or infections.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for testing. If you’re on blood-thinning medication or have a history of clotting issues, your doctor may adjust your care before testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

LDH is a critical marker for assessing tissue injury or disease activity, helping doctors diagnose and manage conditions that affect cell health and energy metabolism.

Short name

LDH Activity

Frequently asked questions

What does an abnormal LDH level mean for my health?
An abnormal LDH level doesn’t have a single cause—it can reflect widespread cell damage, organ stress, or underlying diseases. Your doctor will discuss your results with you and may recommend further tests or treatments based on your symptoms and medical history.
How long does it take to get LDH test results?
Results are typically available within 24 to 48 hours, depending on your lab’s processing times. Your doctor will contact you once they’re ready to review them with you.
Can lifestyle changes affect LDH levels?
While diet and exercise can influence overall health, they don’t typically alter LDH levels on their own. However, managing conditions like heart disease, liver problems, or infections may indirectly affect your test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy