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Lipoprotein(a) concentration (Lp(a))

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-like particle that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) levels can help assess cardiovascular risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44395-2
Short code
Lambda LC 24h Ur Ql
Synonyms
Lambda LC 24h Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares some similarities with LDL (low-density lipoprotein), it behaves differently in the body and is linked to higher risks of blood clots and heart disease. Elevated levels may indicate a genetic predisposition to cardiovascular issues.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a family history of heart disease, stroke, or blood clots, or if you have other risk factors like high blood pressure or diabetes. It may also be used to monitor treatment effectiveness in certain conditions.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab for analysis using a specialized immunoassay method to measure lipoprotein(a) concentration.

What Do Results Mean?

Results are reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While reference ranges vary by lab, higher-than-normal levels may signal increased cardiovascular risk, though individual interpretation depends on overall health and other factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipoprotein(a) Level

Frequently asked questions

What Are Common Causes of Elevated Lipoprotein(a)?
Elevated lipoprotein(a) levels are often genetic and cannot be fully controlled by lifestyle changes alone. However, certain conditions or medications (like some cholesterol-lowering drugs) may influence levels. If your results are high, your provider may discuss genetic testing or other strategies to manage risk.
How Often Should I Get This Test?
There is no standard schedule for this test. Your healthcare provider will determine if and when to repeat it based on your individual risk profile, medical history, and other test results. Regular cardiovascular screenings may include this test if applicable.
Can Diet or Exercise Lower Lipoprotein(a)?
While diet and exercise primarily affect LDL and HDL cholesterol, they may indirectly influence cardiovascular risk by improving overall heart health. There is limited evidence that lifestyle changes can significantly lower lipoprotein(a) levels, but maintaining a healthy weight, managing blood pressure, and quitting smoking are still important for reducing cardiovascular risk factors.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy