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Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a), a type of cholesterol-like substance in your blood that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher heart disease risk and may need monitoring if you have a family history of cardiovascular issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88303-3
Short code
Lambda LC 24h Ur Ql IFE
Synonyms
Lambda LC 24h Ur Ql IFE
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares some traits with regular cholesterol, it behaves differently in the body and may contribute to plaque buildup in arteries more than other fats. This test helps assess your risk for conditions like heart attack or stroke, especially if you have a history of high cholesterol or family history of cardiovascular disease.

Why Might You Need This Test?

Your doctor may order this test if you have a higher risk of heart disease, such as if you have: - A family history of heart disease or stroke - High cholesterol or other risk factors for cardiovascular issues - Conditions like diabetes or high blood pressure It may also be used to monitor treatment progress if you’re already at higher risk.

How Is the Test Performed?

A small blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed to measure the exact amount of lipoprotein(a) in your blood.

What Do the Results Mean?

Results show your lipoprotein(a) level in milligrams per deciliter (mg/dL). Higher levels may indicate an increased risk of heart disease, but this depends on other health factors. Your doctor will discuss the results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lipoprotein(a) [Lp(a)]

Frequently asked questions

Why was this test ordered?
Your doctor may have ordered this test to evaluate your risk for heart disease, especially if you have a family history of cardiovascular problems or other risk factors like high cholesterol. Lipoprotein(a) levels can sometimes be harder to lower than traditional cholesterol, so knowing yours helps guide treatment decisions.
What does a high lipoprotein(a) level mean?
A high lipoprotein(a) level may increase your risk of heart disease or stroke, but it doesn’t mean you’ll definitely develop these conditions. Your doctor will consider your overall health, including other risk factors like blood pressure, diabetes, and lifestyle habits, when interpreting your results.
Can lipoprotein(a) be lowered?
While lifestyle changes like diet and exercise can help manage other risk factors, there is no specific medication to lower lipoprotein(a) levels. Some studies suggest certain medications (like PCSK9 inhibitors) may help, but this is still being researched. Your doctor will discuss the best approach for you.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy