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Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a), a type of cholesterol-related protein that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher cardiovascular risks and may require monitoring if you have a family history of heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10499-2
Short code
Lambda LC Ag Tiss Ql ImStn
Synonyms
Lambda LC Ag Tiss Ql ImStn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares some similarities with LDL (low-density lipoprotein), it behaves differently in the body and is associated with increased risk for blood clots and heart disease. Elevated levels may be harder to treat with standard cholesterol-lowering medications alone.

Why Might You Need This Test?

Your doctor may order this test if you have a history of heart disease, stroke, or blood clots, or if you have a family history of these conditions. It may also be recommended for people with high cholesterol or those undergoing risk assessments for cardiovascular health.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using an immunoassay method to measure lipoprotein(a) levels.

What Does the Test Result Mean?

Results are reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While specific reference ranges vary by lab, higher-than-normal levels may indicate an increased risk for cardiovascular events. Your doctor will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Lipoprotein(a) and Heart Health

Short name

Lipoprotein(a) (Lp(a))

Frequently asked questions

What are the normal results for this test?
There are no universally standardized reference ranges for lipoprotein(a). Results are evaluated based on your individual health profile, including family history, other risk factors, and medical conditions. Your doctor will discuss what your results mean for you.
Can lifestyle changes lower lipoprotein(a) levels?
While lifestyle changes like diet, exercise, and smoking cessation can improve overall heart health, they may not significantly lower lipoprotein(a) levels. Some medications, such as PCSK9 inhibitors, may help in certain cases, but this depends on individual circumstances and should be guided by your healthcare provider.
Is lipoprotein(a) tested in the same way as cholesterol?
Yes, lipoprotein(a) is measured using a blood sample, but it is not included in standard cholesterol panels. It requires a separate test and may be ordered specifically if your doctor suspects elevated levels based on your risk factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy