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Total Immunoglobulin E (IgE) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39552-5
Short code
Lamb IgE/IgE total %
Synonyms
Lamb IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens like pollen, dust, or certain foods. While it’s important for defending against parasites, high levels can trigger allergic reactions such as hives, asthma, or hay fever.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms of allergies, asthma, or other allergic conditions. It can also help diagnose conditions like allergic rhinitis, eczema, or certain immune disorders.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab, where it is analyzed to measure the total IgE concentration using a specialized immunoassay method.

What Do Results Mean?

Results are compared to standard reference ranges, but exact values can vary by lab. High IgE levels may suggest allergies or immune-related conditions, while normal or low levels may indicate fewer allergic responses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

How often will I need this test?
This test may be repeated if your symptoms change or if your doctor needs to monitor your condition over time. Follow-up tests are often based on individual treatment plans and medical history.
What are the possible side effects of the blood draw?
You may experience mild discomfort or bruising at the injection site, but most people have no serious side effects. A cold compress can help reduce swelling or pain.
Can I eat or drink before this test?
Typically, you can eat and drink normally before this test unless your doctor specifies otherwise. Some tests may require fasting, but this test does not.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy