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Laminin Alpha-1 Serum Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of laminin alpha-1 protein in your blood serum. Laminin is a structural protein found in connective tissues and plays a role in cell adhesion and tissue integrity.

Quick summary

["Understanding your laminin alpha-1 levels may help assess connective tissue health or certain genetic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
19114-8
Short code
Lamellar Bod # Amn
Synonyms
Lamellar Bod # Amn
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal laminin levels, such as connective tissue disorders, genetic syndromes, or suspected metabolic or structural protein deficiencies. It could also be part of a broader evaluation for unexplained tissue abnormalities or genetic testing.

What Does This Test Measure?

Laminin alpha-1 is a component of the extracellular matrix, a network of fibers and proteins that provide structural support to cells and tissues. This test specifically quantifies its concentration in your blood serum, which can reflect its availability and potential functional impact in your body.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum (the liquid part after clotting) for testing. This test does not require fasting, but follow your provider’s instructions for any specific preparation.

What Are Possible Results?

Results are presented as a mass concentration (typically in grams per liter or milligrams per deciliter). While reference ranges vary by lab, abnormal results may indicate conditions affecting laminin production, storage, or tissue function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated or reduced laminin alpha-1 levels may signal underlying conditions such as certain genetic disorders (e.g., laminin-related connective tissue diseases), metabolic disorders, or conditions affecting extracellular matrix integrity. These findings may guide further diagnostic testing or treatment planning, especially if symptoms like skin fragility, joint issues, or organ dysfunction are present.

Short name

Laminin Alpha-1 (Serum)

Frequently asked questions

What does a low or high result mean?
A low result could suggest a genetic disorder, metabolic issue, or impaired production of laminin alpha-1. A high result may indicate conditions where laminin is overproduced or improperly regulated, though this is less common. Neither result alone typically diagnoses a condition without clinical correlation.
How often will I need this test?
Frequency depends on your health status, symptoms, and provider recommendations. Some patients may need this test periodically if they have a known condition affecting laminin or if monitoring is part of ongoing care.
Can lifestyle changes affect this test?
While lifestyle factors like diet or exercise may influence overall health, they typically do not directly alter laminin alpha-1 levels. However, maintaining a healthy lifestyle can support general well-being, which may indirectly benefit your body’s ability to manage related conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy