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Laminin alpha-1 chain (serum/plasma) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of laminin alpha-1, a protein found in blood serum or plasma. It may be used to assess certain genetic conditions or protein-related disorders.

Quick summary

["Laminin alpha-1 levels can help diagnose or monitor conditions affecting protein structure in blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17044-9
Short code
Lamellar Bod Amn Ql
Synonyms
Lamellar Bod Amn Ql
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or a family history suggesting conditions like **Ehlers-Danlos syndrome (EDS)** or other connective tissue disorders. It may also be part of genetic testing for protein-related genetic disorders.

What to Expect Before the Test

No special preparation is needed, but you may fast for 8–12 hours before the draw if instructed. Bring your provider’s instructions to confirm details.

What the Test Involves

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. The sample is sent to a lab for analysis.

What the Results Mean

Results are compared to a reference range for healthy adults. Abnormal levels may indicate genetic mutations, protein disorders, or other underlying health concerns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Laminin alpha-1 is part of the extracellular matrix, supporting tissue structure. Low or altered levels may signal genetic disorders affecting collagen or connective tissue, such as **EDS** or **Marfan syndrome**. Always discuss results with your provider for personalized interpretation.

Short name

Laminin α1 (Serum/Plasma)

Frequently asked questions

What causes abnormal laminin alpha-1 levels?
Abnormal levels may result from inherited genetic mutations, certain connective tissue disorders, or metabolic conditions. Rarely, it could be linked to kidney disease or protein loss syndromes.
How is this test different from other protein tests?
Unlike general protein panels, this test specifically measures laminin alpha-1, a niche protein in blood. It’s often used in specialized genetic testing rather than routine screening.
Can lifestyle changes affect this test?
No direct lifestyle factors are known to alter laminin alpha-1 levels, but genetic disorders causing abnormal results are not influenced by diet or exercise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy