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Lanthanum Plasma Protein Electrophoresis (Lanthanum-Based Protein Fractionation)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution in your plasma using a specialized technique that separates different protein types, which can help identify abnormalities in protein composition.

Quick summary

["Assessing protein patterns in your blood for potential health concerns like protein disorders or metabolic issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55786-8
Short code
LA Nt HPL imm 1:2 Plat lysate PPP
Synonyms
LA Nt HPL imm 1:2 Plat lysate PPP
Category
hematology
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
Method
coag
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a method called lanthanum-based protein fractionation to analyze the concentration and distribution of various proteins in your plasma. This helps identify shifts in protein profiles that may indicate underlying conditions affecting protein synthesis, breakdown, or transport.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal protein levels, such as liver disease, kidney problems, or certain genetic disorders. It’s also used in research or specialized diagnostic scenarios where detailed protein profiling is needed.

How the Test Works

A small blood sample is drawn, and the plasma is processed through a lanthanum-based system that separates proteins based on size, charge, or other characteristics. The results provide a profile of protein fractions, which can be compared to typical patterns for evaluation.

Preparation for the Test

No special preparation is needed, but avoid heavy meals or excessive alcohol before your blood draw. Fasted samples may be preferred depending on your provider’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein profiles detected by this test can signal conditions like hypoalbuminemia (low albumin), dysproteinemias (abnormal protein synthesis), or metabolic disorders. It may also help monitor treatment responses in patients with chronic conditions affecting protein metabolism.

Short name

Lanthanum Protein Profile

Frequently asked questions

What causes abnormal protein patterns in this test?
Abnormal protein patterns can result from conditions like liver disease, kidney failure, certain cancers (e.g., multiple myeloma), or genetic disorders. It may also reflect metabolic stress, inflammation, or medications that alter protein levels.
How long does it take to get results?
Results are typically available within 24 to 72 hours, depending on lab processing times and whether additional confirmatory testing is needed.
Can I eat or drink before this test?
Follow your healthcare provider’s instructions, but generally, light fasting or avoiding heavy meals may be recommended to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy